Unmatched Biocompatibility:

BIOLOX® Ceramics causes no known
allergic reactions

In selecting the most suitable wear couple for active patients it is necessary to consider the osteolytic potential of the respective pairing. Compared to other wear couples, ceramic wear couples generate wear debris with the lowest biological activity level.

Unmatched Biocompatibility:
BIOLOX® Ceramics causes no known allergic reactions

“The use of ceramic wear couples for artificial hip joints is recommended in medical literature because of the minimal wear and excellent biocompatibility.”

Major biocompatibility testing of wear and corrosion resistant BIOLOX® ceramics was conducted as early as the 1970s. More than 40 years of clinical experience and a large number of histological investigations done by various groups have demonstrated the superior biocompatibility and excellent long-term clinical performance of BIOLOX® ceramic implants. BIOLOX® ceramics do not release metal ions and do not cause undesirable allergic reactions. The use of ceramic wear couples for artificial hip joints is recommended in medical literature in preference to metal/polyethylene wear couples on account of their exceptionally low wear and excellent biocompatibility. This is especially an advantage for young and active patients due to their high level of physical activity which places higher demands on the materials used.

Metal Sensitivity reduces the Life of the Implant

“Allergic reactions to metal implants can result in the removal or replacement of the implants.”

An ever increasing number of publications report on allergic reactions to the constituents of the metal alloys used in both hip and knee replacements. Metallic elements such as nickel, chromium and cobalt are well-known contact allergens, which can cause allergic reactions in the human body. Medical literature contains innumerable articles which report on the immune response and hypersensitivity reactions to metals and their effect on the life expectancy and/or failure of implants. Immunological and allergic reactions to the metallic constituents of metal alloys are cited as possible causes for osteolysis, early implant loosening and postoperative complications such as delayed wound healing, delayed bone healing and eczema. Allergic reactions to metal implants can result in the removal or replacement of the implants.

The Possibility of Health Risks due to metallic Wear cannot be excluded

The use of a metal/metal prosthesis is not recommended in medical literature for patients with metal allergies and chronic kidney disease. It is unclear as to the possible side effects caused by long-term exposure of the human body to minute metallic wear debris and metal ions. Specialists are still not certain whether released metal ions have a tumor-causing effect. However, some publications have raised the suspicion that a weakening of the body’s own resistance to infection is one possible effect for patients caused by this disturbance to the immunological system.

The Choice of Materials is becoming increasingly important

As publications show, there is still no reliable diagnostic test which can be used to predict whether there will be an allergic reaction to the metal elements in orthopedic implants. In view of this uncertainty and on account of reports showing an increasing number of patients who exhibit hypersensitivity reactions to metals, the choice of materials for the wear couple in artificial joints becomes even more important.

Recommended Contacts

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